{"product_id":"target-gb-x","title":"Ther-Biotic Target gb-X","description":"\u003ch4\u003eBenefits and Features\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003ePowered by Ecologic BARRIER, a 5B CFU blend of 9 probiotic strains \u003c\/li\u003e\n\u003cli\u003eProtected by PROBIOACT® Technology for optimal efficacy and shelf-stability \u003c\/li\u003e\n\u003cli\u003eHypoallergenic, non-GMO powder in single-serving sachets \u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eClinically shown to support positive mood by influencing the gut-brain axis through the microbiome.\u003csup\u003e†\u003c\/sup\u003e\u003c\/p\u003e\n\u003ch4\u003eDetail Overview\u003c\/h4\u003e\n\u003cp\u003eTarget gb-X™ is a probiotic supplement specifically designed to support positive mood by influencing the gut-brain axis through the microbiome. It is powered by Ecologic BARRIER, a 5B CFU blend of 9 probiotic strains, that has been clinically shown to decrease overall cognitive reactivity to sad mood, rumination, negative thoughts, and aggressive thoughts.\u003csup\u003e1\u003c\/sup\u003e Heightened cognitive reactivity to sad mood is an established risk factor for more serious mood alterations in otherwise healthy individuals and is therefore considered an important target for interventions.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eTarget gb-X™ Mechanism \u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eTarget gb-X™ with Ecologic BARRIER was specifically designed to influence the gut-brain axis through defined mechanisms including strengthening of the gut barrier function, modulation of cytokines and inflammatory response, production of potentially neuroprotective metabolites, and HPA regulation. Preclinical research emphasized a pronounced shift away from macrophage-produced cytokines to T-lymphocyte-produced cytokines, a reduction in circulating lipopolysaccharide endotoxins, and a marked reduction in transcription of hippocampal genes related to HPA regulation.\u003csup\u003e2\u003c\/sup\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProbiotics and the Gut-Brain Axis \u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThe gut-brain axis refers to the bidirectional communication network between the central and autonomic nervous systems and the intestines. Gut-brain communications are mediated by the immune system, endocrine connections such as the hypothalamic-pituitary-adrenal (HPA) axis, and neural pathways involving the enteric nervous system. The gut microbiota is now known to play a pivotal role in gut-brain communications. It is a complex interaction whereas the microbiota engages locally with intestinal cells as well as communicating directly with the central nervous system through neuroendocrine, immune, and metabolic pathways.\u003csup\u003e3\u003c\/sup\u003e Research into gut-brain mechanisms is rapidly expanding our understanding and serves to inform the development of targeted probiotic formulations.\u003c\/p\u003e","brand":"SFI Health","offers":[{"title":"30 Sachets","offer_id":47394298036313,"sku":null,"price":45.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2219\/7335\/files\/GBX_Box_webv2.png?v=1791386445","url":"https:\/\/store.atlantafunctionalmedicine.com\/products\/target-gb-x","provider":"Atlanta Functional Medicine","version":"1.0","type":"link"}