NAC & ALA

• Provides relevant amounts of both N-acetyl-L-cysteine and alpha-lipoic acid
• NAC and ALA are involved in antioxidant activity, and maintain the normal synthesis and regeneration of glutathione, the key cellular antioxidant*
• Supports healthy mitochondrial function as well as normal phase 2 antioxidant enzyme activity*
• Supports normal endothelial function and maintains nitric oxide synthesis already within the normal range*

N-acetylcysteine (NAC) and alpha-lipoic acid (ALA) are highly complementary nutrients. Together, they support the clearing of normal cellular debris and maintain normal cellular function. NAC helps maintain the healthy synthesis of glutathione, and antioxidant activity.^1,2 NAC also helps support the normal restoration of intracellular thiols, and helps clear normal cellular debris via the maintenance of nuclear factor kappa B (NF-κB).³ Glutathione is needed to detoxify the body’s natural toxins, and maintain adipose tissue metabolism.⁴ In addition to glutathione support, NAC supports antioxidant activity through multiple pathways, including nuclear factor (erythroid-derived 2)-like 2 (Nrf2) and phosphoinositide 3-kinase/protein kinase B (PI3K/AKT).⁵ NAC helps support healthy endothelial function and maintain homocysteine already within the normal range.^6,7
ALA, in turn, recycles important nutrients such as vitamin C and glutathione. It is a cofactor for several mitochondrial enzymes as well as glutathione reductase.⁸ ALA helps maintain healthy glycemic control, normal insulin sensitivity, and healthy endothelial function, as well as healthy weight maintenance.^9,10,11 ALA supports healthy glucose levels already within the normal range.^12,13 ALA may support healthy oxidative status in a variety of populations.^14,15 By supporting antioxidant activity, it may also help maintain normal neuronal function.^16,17