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Phyto-4
Phyto-4
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Phyto-4

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  • Promotes joint health & comfort
  • Supports healthy immune response
  • Provides support for connective tissue structural composition
  • Includes clinically researched botanicals
  • Made with high-quality vegan ingredients backed by verifiable science

 

Verifiable Science

Perluxan® is a clinically studied extract of hops specifically developed to promote joint health. In a randomized, double-blind, placebo-controlled trial of 36 subjects, the benefits of Perluxan® on joint comfort reached statistical significance within two hours of the first dose and were sustained over the 14-day period. Perluxan® is free of sleep-inducing and phytoestrogenic compounds typically associated with hops extracts.1 The alpha and iso-alpha acids in Perluxan® maintain healthy NF-kappa B-associated expression of COX-2 and cytokines such as IL-6 and TNFα in connective tissue.2 Curcumin complements Perluxan® through its extensively characterized effects on cytokine-mediated signal transduction, matrix metalloproteinase (MMP) expression and multiple components of the arachidonic acid cascade.3 Curcumin C3 Complex® is the subject of extensive ongoing clinical investigations at numerous hospitals and universities.4 Ginger promotes joint health through maintaining healthy cytokine signaling in cartilage and the synovium.5 5LOXIN® Boswellia serrata extract provides the highly bioactive triterpenoid AKBA, which supports connective tissue structural composition and comfort through supporting healthy immune responses, 5-lipoxygenase activity and synovial matrix metalloproteinase 3 (MMP-3) levels.6,7 In a 3-month double-blind, placebo-controlled study of 75 subjects, significant functional support and comfort scores were evident as early as day 7.8‡